A Paradigm Shift To Prevent And Treat Alzheimer S Disease

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Author: Howard Friel
Publisher: Academic Press
ISBN: 012812279X
Size: 50.88 MB
Format: PDF
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A Paradigm Shift To Prevent And Treat Alzheimer S Disease by Howard Friel

Original Title: A Paradigm Shift To Prevent And Treat Alzheimer S Disease

A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers. Presents carefully compiled evidence supporting the need to shift from pharmaceutical-based mono-targeting to plant polyphenol-based pleiotropic targeting for the prevention and treatment of Alzheimer’s disease Includes valuable tables that aggregate pleiotropic pharmacological effects of the plant polyphenols on Alzheimer’s disease-related pathogenic hallmarks Highlights regulatory aspects and discusses the challenges and potential solutions with respect to bioavailability of certain plant polyphenols

The End Of Alzheimer S

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Author: Dale Bredesen
Publisher: Penguin
ISBN: 0735216223
Size: 45.18 MB
Format: PDF, Kindle
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The End Of Alzheimer S by Dale Bredesen

Original Title: The End Of Alzheimer S

The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.

Alzheimer S Disease

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Author: Harald Hampel
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805598025
Size: 44.66 MB
Format: PDF, Docs
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Alzheimer S Disease by Harald Hampel

Original Title: Alzheimer S Disease

How current biomarkers are modernizing the diagnosis of Alzheimer's disease Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer's disease. In this publication, leading experts discuss emerging novel conceptual models of the disease along with advances in the development of surrogate markers that will not only improve the accuracy of diagnostic technologies but also improve the prospects of developing disease-modifying interventions. The novel framework of the disease presented here highlights research on biological markers as well as efforts to validate technologies for early and accurate detection. It also introduces notion of a complex systems dysfunction that extends beyond prevailing ideas derived from the amyloid' or tau' hypotheses. This outstanding publication provides researchers, clinicians, students and other professionals interested in neurodegenerative disorders with a comprehensive update on current trends and future directions in therapy development, with special focus on advances in clinical trial designs.

Why Buddha Never Had Alzheimer S

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Author: Shuvendu Sen
Publisher: Health Communications, Inc.
ISBN: 0757319947
Size: 28.33 MB
Format: PDF, Kindle
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Why Buddha Never Had Alzheimer S by Shuvendu Sen

Original Title: Why Buddha Never Had Alzheimer S

Who among us is not affected by issues such as stress, depression, personality and behavioral changes, agitation, hypertension or high cholesterol--to name a few? Did you know that these are some of the cognitive and biological deficiencies that are associated with Alzheimer's? It is estimated that 5.4 million people in the U.S. are afflicted with Alzheimer's disease. In its capacity to completely destroy personalities, relationships and daily living, we cannot afford to continue thinking of it as a private disease. Alzheimer's is a family problem--ruthless in its scope and spread. And despite relentless trials and research studies, scientists have not found a drug to control it. Even worse, there isn't even a fully reliable diagnostic test for it. Alzheimer's disease has become a gigantic specter that looms before all of us as we age, and it is advancing unimpeded. Today we know that contributing factors and symptoms (such as stress and hypertension) can be alleviated with holistic, alternate management approaches--like meditation, yoga, music therapy and virtual reality therapy. Research studies from Harvard Medical School, Johns Hopkins University and Mayo Clinic, among many others, have demonstrated the comprehensive benefits of yoga and meditation on various aspects of the human mind--and when you think about it, that's where Alzheimer's disease develops--in the mind. But, how can meditation and yoga stop or even reverse the course of Alzheimer's? They set the mind on an inward journey where the risk factors that precipitate the disease are formed. This bridging of the old and new creates an imperative paradigm shift in our perspective toward Alzheimer's disease management. Why Buddha Never Had Alzheimer's is precisely what is needed to cause a drastic and necessary revolution in medical care.

Ferri S Clinical Advisor 2015

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Author: Fred F. Ferri
Publisher: Elsevier Health Sciences
ISBN: 0323084303
Size: 68.33 MB
Format: PDF
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Ferri S Clinical Advisor 2015 by Fred F. Ferri

Original Title: Ferri S Clinical Advisor 2015

Ferri’s Clinical Advisor 2015 is the fastest, most effective way to access current diagnostic and therapeutic information on more than 700 common medical conditions. Dr. Ferri’s popular "5 books in 1" format provides quick guidance on short QT syndrome, microscopic polyangiitis, fungal meningitis, and much more. This medical reference makes the answers you need even easier to find - anytime, anywhere. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Review normal values and interpret results for more than 200 lab tests. Improve your family healthcare practice’s efficiency with cost-effective referral and consultation guidelines. Identify and treat a broader range of disorders, including diabetic foot infections, hypergonadism, and acute liver failure, with 22 new topics in the Diseases & Disorders section. Improve your interpretation of presenting symptoms with 38 new topics and 40 new images in the Differential Diagnosis section, and optimize patient care with more than 250 new figures and tables. Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets, tables, boxes, and algorithms to expedite your search. Expedite insurance reimbursements with current ICD-9 and future ICD-10 insurance billing codes. Access full-color images and more than 90 online-only topics at Expert Consult, as well as EBMs, Suggested Reading, Patient Teaching Guides, and additional algorithms.

Managing Memory Clinical Facts Biomedical Negotiations And Alzheimer S Identities

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Author: Renee Lynn Beard
Size: 69.18 MB
Format: PDF, Mobi
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Managing Memory Clinical Facts Biomedical Negotiations And Alzheimer S Identities by Renee Lynn Beard

Original Title: Managing Memory Clinical Facts Biomedical Negotiations And Alzheimer S Identities

Methods. 18 months of participant observation at two specialty clinics, including 46 diagnoses of AD or MCI, qualitative interviews, and focus groups were conducted. Data were analyzed using Grounded Theory. The complete sample included 77 respondents: focus groups with 32 diagnosed individuals, focus groups with 12 care partners of diagnosed individuals, and 33 in-depth interviews (12 clinicians, 12 Alzheimer's Association staff members, and 9 diagnosed individuals).

Treating Dementia

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Author: Jesse F. Ballenger
Size: 60.59 MB
Format: PDF, ePub, Docs
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Treating Dementia by Jesse F. Ballenger

Original Title: Treating Dementia

Treatments for age-related dementia and the growing reliance on pharmaceuticals to alleviate its worst symptoms raise a number of questions about attitudes toward aging and cognition, the relationship between growing older and getting sick, and the conflicting interests of patients, caregivers, physicians, scientists, and business. This volume aims to foster a constructive debate about the future of dementia treatment by providing multiple perspectives on these tangled issues. The first section examines how the concepts of dementia have expanded to encompass a broad range of symptoms and the implications of this evolution on the development of pharmaceutical treatments. The second section explores the use and effectiveness of drug treatments for dementia through the perspectives of a clinician, a researcher, and a layperson. In the third section, the contributors probe how culture, language, and values affect the overlapping worlds of pharmacology, drug marketing, and dementia treatment. A final section elucidates the thorny ethical and policy concerns surrounding the often-conflicting hopes for dementia medications. Featuring contributions from noted clinicians, researchers, and scholars from a broad range of disciplines, this multidisciplinary dialogue addresses central questions about the history and future of drug treatment for dementia and makes clear why there are no simple answers. Professionals and students involved in gerontology, psychiatry, and bioethics will find the discussion both enlightening and practical.

Public Health Nursing

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Author: Marcia Stanhope
Publisher: Elsevier Health Sciences
ISBN: 0323294103
Size: 67.49 MB
Format: PDF, ePub, Mobi
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Public Health Nursing by Marcia Stanhope

Original Title: Public Health Nursing

Now in its 8th edition, the "gold standard" in community health nursing provides comprehensive and up-to-date content to keep you at the forefront of the ever-changing community health climate and prepare you for an effective nursing career. In addition to a solid foundation in concepts and interventions for individuals, families, and communities, you will find real-life applications of the public nurse's role, Healthy People 2020 initiatives, new chapters on forensics and genomics, plus timely coverage of disaster management and important client populations such as pregnant teens, the homeless, immigrants, and more. Evidence-Based Practice boxes illustrate how the latest research findings apply to public/community health nursing. Separate chapters on disease outbreak investigation and disaster management describe the nurse's role in surveilling public health and managing these types of threats to public health. Separate unit on the public/community health nurse's role describes the different roles and functions of the public/community health nurse within the community. Levels of Prevention boxes show how community/public health nurses deliver health care interventions at the primary, secondary, and tertiary levels of prevention. What Do You Think?, Did You Know?, and How To? boxes use practical examples and critical thinking exercises to illustrate chapter content. The Cutting Edge highlights significant issues and new approaches to community-oriented nursing practice. Practice Application provides case studies with critical thinking questions. Separate chapters on community health initiatives thoroughly describe different approaches to promoting health among populations. Appendixes offer additional resources and key information, such as screening and assessment tools and clinical practice guidelines. Linking Content to Practice boxes provide real-life applications for chapter content. NEW! Healthy People 2020 feature boxes highlight the goals and objectives for promoting health and wellness over the next decade. NEW! The Nurse in Forensics chapter focuses on the unique role of forensic nurses in public health and safety, interpersonal violence, mass violence, and disasters. NEW! Genomics in Public Health Nursing chapter includes a history of genetics and genomics and their impact on public/community health nursing care.

Abnormal Psychology And Modern Life

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Author: Robert C. Carson
Publisher: Longman
ISBN: 9780321034304
Size: 79.20 MB
Format: PDF, Mobi
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Abnormal Psychology And Modern Life by Robert C. Carson

Original Title: Abnormal Psychology And Modern Life

The eleventh edition of Abnormal Psychology and Modern life retains it's focus on the authoritative overview of contemporary and classic research within a more accessible framework. Features supporting this aim include upstaed research, intergrated mulitcultual and cross-cultural research, accessible organization, highlight sections, unresolved issues sections and case studies. *Expanded research with a focus on biological and cultural influences on psychological disorders including over 1500 new references. A detailed list of new research in each chapter can be found in the texts Preface. *Integrated multicultural and cross-cultural research in each chapter includes coverage of sociocultural causal factors in Chapter 3, cross-cultural differences in depressive symptoms in Chapter 6, sociocultural factors in alcohol abuse and dependence in Chapter 10, and psychotherapy and multiculturalism in Chapter 17, highlighting the important issue of racial/ethnic mismatches between therapist and client. *Highlight: Modern Life sections apply research to students everyday lives and make research more accessible. Highlight: Cutting Edge sections feature research methodology and recent findings

Carranza S Clinical Periodontology

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Author: Michael G. Newman
Publisher: Elsevier Health Sciences
ISBN: 0323227996
Size: 37.95 MB
Format: PDF, Mobi
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Carranza S Clinical Periodontology by Michael G. Newman

Original Title: Carranza S Clinical Periodontology

The most widely used periodontics text, Carranza's Clinical Periodontology provides both print and online access to basic procedures as well as the latest in advanced procedures and techniques in reconstructive, esthetic, and implant therapy. Not only does this book show how to do periodontal procedures, it describes how to best manage the outcomes and explains the evidence supporting each treatment. Written by leading experts Michael Newman, Henry Takei, Perry Klokkevold, and Fermin Carranza, along with a pool of international contributors, this edition also discusses the close connection between oral health and systemic disease. A new Expert Consult website includes the entire, fully searchable contents of the book, and takes learning to a whole new level with content updates, videos, a drug database, and much more. Comprehensive coverage describes all aspects of periodontics in a single volume, including periodontal pathology, the etiology of periodontal diseases, the relationship between periodontal disease and systemic health, treatment of periodontal diseases, oral implantology, supportive treatment, and ethics, legal, and practical matters. Problem-solving, scenario-based learning opportunities use well-documented case reports to help you learn both basic and advanced procedures and techniques. 'Speed to competence' is enhanced with access to print, online, and mobile platforms. A unique approach combines evidence-based decision-making, science transfer, and classification/nomenclature throughout every chapter. A one-of-a-kind Genetic Factors and Periodontal Disease chapter examines the role of genetic factors in gum disease. In-depth information serves as an excellent foundation in preparing for the National Board Dental Exam. Coverage of the latest advances includes the emerging link between periodontal disease and systemic health. Full-color illustrations depict the newest developments in surgical technology. A new Multidisciplinary Approach to Dental and Periodontal Problems chapter discusses the importance of collaborative care in the practice of periodontics. Etiology of Periodontal Diseases (Part 4) provides a more comprehensive background in periodontal anatomy, physiology, and pathogenesis.

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