The Osteoporotic Syndrome

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Author: Louis V. Avioli
Publisher: Elsevier
ISBN: 9780080542577
Size: 20.51 MB
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The Osteoporotic Syndrome by Louis V. Avioli


Original Title: The Osteoporotic Syndrome

Metabolic bone degeneration (osteoporosis) affects millions of people--primarily postmenopausal women--and is directly responsible for debilitating hip, vertebral, and limb fractures in the elderly. Incorporating advances made within just the past five years, The Osteoporotic Syndrome: Detection, Prevention, and Treatment serves as an up-to-date, practical guide to the major clinical aspects of osteoporosis. The text is liberally illustrated with detailed figures. As a resource for the clinician dealing with metabolic bone degeneration, this book represents an excellent source of information on the diagnosis and day-to-day management of osteoporosis. Topics covered include: Therapy with Vitamin D metabolites, sodium fluoride, thiazides, and isoflavones Biochemical markers of bone turnover Calcium, Vitamin D, and bone metabolism Estrogens and tissue selective estrogens for prevention and treatment of osteoporosis The effects of osteoporosis on orthopaedic surgery The therapy of glucocorticoid bone disease Effects of aging on bone structure and metabolism Management of osteoporotic patients in our health care delivery system The genetics of osteoporosis Bisphosphonate therapy for osteoporosis Calcitonin Bone mass measurement techniques in clinical practice Osteoporosis and the bone biopsy

Metabolic Bone Disease And Clinically Related Disorders

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Author: Louis V. Avioli
Publisher: Academic Press
ISBN: 0080536271
Size: 15.57 MB
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Metabolic Bone Disease And Clinically Related Disorders by Louis V. Avioli


Original Title: Metabolic Bone Disease And Clinically Related Disorders

Metabolic Bone Disease, Third Edition is the new, expanded edition of the classic text, featuring the latest advancements and research information in this fast-moving field. The Third Edition includes the most up-to-date information on molecular mechanisms, basic biology, pathophysiology, and diagnosis and management strategies of metabolic bone disease. Key Features * Edited by "fathers of the field" * An expanded version of a classic AP text * Complete coverage of a fast-growing field

Calcium Regulating Hormones And Cardiovascular Function

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Author: M.F. Crass, III
Publisher: CRC Press
ISBN: 9780849386619
Size: 52.86 MB
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Calcium Regulating Hormones And Cardiovascular Function by M.F. Crass, III


Original Title: Calcium Regulating Hormones And Cardiovascular Function

This is the first book to exclusively address the actions of calcium-regulating hormones and peptides in the cardiovascular system. With 111 illustrations and 13 tables, this comprehensive volume includes: An extensive and critical review of present knowledge of the structure, synthesis, secretion, metabolism, receptors, signal transduction, and actions on classical target cells of each of the calcium-regulating hormones and peptides Discussions on parathyroid hormone and calcitonin, parathyroid hormone-related protein, parathyroid hypertensive factor, 1,25 dihydroxyvitamin D3, calcitonin gene-related peptide, and certain steroid hormones in terms of vascular biology and cardiac function The integrated physiology of calcium-regulating hormones in terms of blood pressure regulation in normotensive and hypertensive settings State-of-the-art electrophysiological techniques used by leading cardiovascular biologists to assess calciotropic hormone effects on calcium channel currents in both vascular smooth muscle and cardiac myocytes Studies on the regulation of hormone and receptor gene expression in the context of possible regulation of local and systemic blood flow and cardiac function by calcium-regulating hormones and peptides

Metabolic Bone Disease

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Author: Louis V. Avioli
Publisher: Academic Press
ISBN: 1483216314
Size: 47.16 MB
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Metabolic Bone Disease by Louis V. Avioli


Original Title: Metabolic Bone Disease

Metabolic Bone Disease, Volume I covers the approach to a variety of disorders of mineral metabolism. The book discusses bone metabolism and calcium regulation; kidney function in calcium and phosphate metabolism; as well as the role of alkaline phosphatase in metabolic bone disorders. The text also describes the diagnostic value of bone biopsies; the etiology, clinical aspects, therapy, and the main syndromes of vitamin D deficiency, rickets, and osteomalacia; and the pathogenesis and therapy of osteoporosis. The pathogenesis and treatment of nephrolothiasis are also encompassed. Orthopedic doctors, physicians, endocrinologists, and people involved in the research of metabolic bone diseases will find the book invaluable.

Vitamin D

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Author: Michael F. Holick
Publisher: Springer Science & Business Media
ISBN: 9781603273039
Size: 53.38 MB
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Vitamin D by Michael F. Holick


Original Title: Vitamin D

In Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition, leading researchers provide a comprehensive, highly readable overview of the biological functions and clinical applications of vitamin D and its metabolites. Topics range from the most recent recommendations for vitamin D intake to new approaches for the treatment and prevention of vitamin D deficiency and the development of active vitamin D drugs to treat psoriasis and cancer. The book demonstrates the significant role that vitamin D has in maintaining good bone health and the prevention of osteoporosis, an important health problem for adults over the age of fifty. In addition, it authoritatively reviews the relationship between sunlight exposure, vitamin D, and increased risk of colon and breast cancer; how vitamin D is made in the skin; and the sequence of events that leads to its activation by the kidney. Also examined are the biological functions of 1,25-dihydrovitamin D3 on the intestine and bone, as well as other tissues, such as skin, the immune system, prostate, and breast, and vitamin D's molecular mechanism of action on the cell membrane and nucleus. The first edition of Vitamin D: Physiology, Molecular Biology and Clinical Applications was the benchmark in the field when published in 1999. This new and expanded volume continues to include extensive, in-depth chapters covering the most important aspects of the complex interactions between vitamin D and other dietary components, the ongoing debate concerning the best indicator of optimal vitamin D status and its nutrient requirements, and the impact of less than optimal status on disease risk. Vitamin D: Physiology, Molecular Biology, and Clinical Applications, Second Edition is designed and organized not only to be an up-to-date review on the subject, but also to provide medical students, graduate students, health care professionals and even the lay public with a reference source for the most up-to-date information about the vitamin D deficiency pandemic and its clinical implications for health and disease.

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