Kinetic Modelling In Systems Biology

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Author: Oleg Demin
Publisher: CRC Press
ISBN: 9781420011661
Size: 76.29 MB
Format: PDF
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Kinetic Modelling In Systems Biology by Oleg Demin


Original Title: Kinetic Modelling In Systems Biology

With more and more interest in how components of biological systems interact, it is important to understand the various aspects of systems biology. Kinetic Modelling in Systems Biology focuses on one of the main pillars in the future development of systems biology. It explores both the methods and applications of kinetic modeling in this emerging field. The book introduces the basic biological cellular network concepts in the context of cellular functioning, explains the main aspects of the Edinburgh Pathway Editor (EPE) software package, and discusses the process of constructing and verifying kinetic models. It presents the features, user interface, and examples of DBSolve as well as the principles of modeling individual enzymes and transporters. The authors describe how to construct kinetic models of intracellular systems on the basis of models of individual enzymes. They also illustrate how to apply the principles of kinetic modeling to collect all available information on the energy metabolism of whole organelles, construct a kinetic model, and predict the response of the organelle to changes in external conditions. The final chapter focuses on applications of kinetic modeling in biotechnology and biomedicine. Encouraging readers to think about future challenges, this book will help them understand the kinetic modeling approach and how to apply it to solve real-life problems. CD-ROM Features Extensively used throughout the text for pathway visualization and illustration, the EPE software is available on the accompanying CD-ROM. The CD also includes pathway diagrams in several graphical formats, DBSolve installation with examples, and all models from the book with dynamic visualization of simulation results, allowing readers to perform in silico simulations and use the models as templates for further applications.

The Biology Of Alcoholism

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Author: Benjamin Kissin
Publisher: Springer Science & Business Media
ISBN: 146840895X
Size: 39.33 MB
Format: PDF, ePub, Mobi
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The Biology Of Alcoholism by Benjamin Kissin


Original Title: The Biology Of Alcoholism

Alcoholism is a uniquely human condition. Although some forms of alcohol dependence can be induced experimentally in a variety of laboratory animals, the complete spectrum of alcoholism with all of its physical, psychological, and social implications occurs only in man. The special quality of this relationship becomes more significant when one considers that the manifestations of most physical disease syndromes in animals and man are more similar than they are different. The uniqueness of alcoholism lies in the fact that it is one of the few physical diseases which reflects at all levels the problems of individuals coping with the complexities of human society. In order to present a more coherent picture of these complex relationships, we have attempted to impose a logical sequence upon the material. This sequence lies along a dual parameter-from the physical to the social and from the theor etical to the empirical. Consequently, it was natural for the first volume in this series to deal with biochemistry, the most basic and physical aspect of the inter action of alcohol and man. It is equally natural for this, the second volume, to deal with physiology and behavior, for these levels of phenomenology-partic ularly the latter-are already more empirical and psychological in their mani festations. Finally, the third volume, clinical pathology, describes the disease itself, with all of the medical and social implications carried in the word "alcoholism.

Computational Structural Biology

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Author: Manuel Claude Peitsch
Publisher: World Scientific
ISBN: 9812778772
Size: 75.15 MB
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Computational Structural Biology by Manuel Claude Peitsch


Original Title: Computational Structural Biology

This work covers the impact of computational structural biology on protein structure prediction methods, macromolecular function and protein design, and key methods in drug discovery. It also addresses the computational challenges of experimental approaches in structural biology.

Human Biology

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Author: Sara Stinson
Publisher: John Wiley & Sons
ISBN: 1118108043
Size: 58.51 MB
Format: PDF, Mobi
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Human Biology by Sara Stinson


Original Title: Human Biology

This comprehensive introduction to the field of human biology covers all the major areas of the field: genetic variation, variation related to climate, infectious and non-infectious diseases, aging, growth, nutrition, and demography. Written by four expert authors working in close collaboration, this second edition has been thoroughly updated to provide undergraduate and graduate students with two new chapters: one on race and culture and their ties to human biology, and the other a concluding summary chapter highlighting the integration and intersection of the topics covered in the book.

Philosophy Of Biology

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Author: Brian Garvey
Publisher: Routledge
ISBN: 1317493672
Size: 48.77 MB
Format: PDF, Kindle
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Philosophy Of Biology by Brian Garvey


Original Title: Philosophy Of Biology

This major new series in the philosophy of science aims to provide a new generation of textbooks for the subject. The series will not only offer fresh treatments of core topics in the theory and methodology of scientific knowledge, but also introductions to newer areas of the discipline. Furthermore, the series will cover topics in current science that raise significant foundational issues both for scientific theory and for philosophy more generally. Biology raises distinct questions of its own not only for philosophy of science, but for metaphysics, epistemology and ethics. This comprehensive new textbook for a rapidly growing field of study provides students new to the subject with an up-to-date presentation of the key philosophical issues. Care is taken throughout to keep the technicalities accessible to the non-biologist but without sacrificing the philosophical subtleties. The first part of the book covers the philosophical challenges posed by evolution and evolutionary biology, beginning with Darwin's central argument in the Origin of the Species. Individual chapters cover natural selection, the selfish gene, alternative units of selection, developmental systems theory, adaptionism and issues in macroevolution. The second part of the book examines philosophical questions arising in connection with biological traits, function, nature and nurture, and biological kinds. The third part of the book examines metaphysical questions, biology's relation with the traditional concerns of philosophy of science, and how evolution has been introduced into epistemological debates. The final part considers the relevance of biology to questions about ethics, religion and human nature.

Humans In Nature

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Author: Gregory E. Kaebnick
Publisher: Oxford University Press
ISBN: 0199347239
Size: 27.98 MB
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Humans In Nature by Gregory E. Kaebnick


Original Title: Humans In Nature

Contemporary debates over issues as wide-ranging as the protection of wildernesses and endangered species, the spread of genetically modified organisms, the emergence of synthetic biology, and the advance of human enhancement, all of which seem to spin into deeper and more baffling questions with every change in the news cycle, often circle back to the same fundamental question: should there be limits to the human alteration of the natural world? A growing number of people view the human capacity to alter natural states of affairs -- from formerly wild spaces and things around us to crops and livestock to our own human nature -- as cause for moral alarm. That reaction raises a number of perplexing philosophical questions, however: Can we identify "natural" states of affairs at all? Does the idea of being morally concerned about the human relationship to nature make any sense? Should such a concern influence public policy and politics, or should government stay strenuously neutral on such matters? Through a study of moral debates about the environment, agricultural biotechnology, synthetic biology, and human enhancement, Gregory E. Kaebnick, a research scholar at The Hastings Center and editor of the Hastings Center Report, argues that concerns about the human alteration of nature can be legitimate and serious, but also that they are complex, contestable, and of limited political force. Kaebnick defends attempts to identify "natural" states of affairs by disentangling the nature/artifact distinction from metaphysical hoariness. Drawing on David Hume, he also defends moral standards for the human relationship to nature, arguing that they, and moral standards generally, should be understood as grounded in what Hume called the "passions." Yet what counts as "natural" can be delineated only roughly, he concludes, and moral standards for interaction with nature are less a matter of obligation than of ideals. Kaebnick also concludes, drawing on an interpretation of the liberal principle of neutrality, that government may support those standards but must be careful not to enforce them. Thus Kaebnick looks for a middle way on debates that have tended toward polarization. "As differences between nature and artifact become steadily less substantial, problems about preservation run to the core of how people can make sense of themselves, of each other, and of our shared world. Kaebnick's solutions are creative and compelling, theoretically elegant and politically practical. Providing distinctive ways forward, when much academic and policy discussion seems exhausted, his book demands wide attention. In return, it inspires hope." - James Nelson, Michigan State University

Assertion Reason Question Bank In Biology For Aiims

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Author: Disha Experts
Publisher: Disha Publications
ISBN: 9387421031
Size: 18.24 MB
Format: PDF, Docs
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Assertion Reason Question Bank In Biology For Aiims by Disha Experts


Original Title: Assertion Reason Question Bank In Biology For Aiims

Assertion-Reason Questions are the most tedious part in the AIIMS examination. They require not only understanding the statements but also the correct and accurate conceptual reasoning. Assertion-Reason Question Bank in Biology for AIIMS provides a comprehensive set of questionnaires to supplement learning from the NCERT textbooks. The book contains, in all, 2000+ questions with 95% + explanations. This book is devised for students to overcome the difficulty faced by them in attempting Assertion and Reason questions. It will help them to refine their concepts and emerge out successful in various competitive medical entrance examinations. This entire book comprises of chapter-wise questions according to the NCERT curriculum. At the end of every chapter, detailed solutions have been provided to help students with self-assessment. The uniqueness of this book lies in the new set of questions providing coverage of the entire NCERT syllabus.

The Mcat Biology Book

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Author: Nancy Morvillo
Publisher: Nova Press
ISBN: 1889057444
Size: 19.74 MB
Format: PDF
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The Mcat Biology Book by Nancy Morvillo


Original Title: The Mcat Biology Book

Comprehensive, Rigorous Prep for MCAT Biology. REVISED FOR MCAT 2015. The MCAT Biology Book provides a comprehensive overview of MCAT biology appropriate for all pre-med students preparing for the MCAT exam. In twenty-one chapters, the basics of biology are described in easy-to-understand text. Illustrations help emphasize relevant topics and clarify difficult concepts. Each chapter concludes with a set of problems modeled after the MCAT exam, with complete explanation of the answers. Also, includes a thorough analysis of the MCAT verbal section. Authors Nancy Morvillo and Matthew Schmidt both obtained their Ph.D. in genetics from the State University of New York at Stony Brook.

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