Quantitative Analysis Of Neuroanatomy

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Author: Julian M L Budd
Publisher: Frontiers Media SA
ISBN: 2889197964
Size: 29.90 MB
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Quantitative Analysis Of Neuroanatomy by Julian M L Budd

Original Title: Quantitative Analysis Of Neuroanatomy

The true revolution in the age of digital neuroanatomy is the ability to extensively quantify anatomical structures and thus investigate structure-function relationships in great detail. Large-scale projects were recently launched with the aim of providing infrastructure for brain simulations. These projects will increase the need for a precise understanding of brain structure, e.g., through statistical analysis and models. From articles in this Research Topic, we identify three main themes that clearly illustrate how new quantitative approaches are helping advance our understanding of neural structure and function. First, new approaches to reconstruct neurons and circuits from empirical data are aiding neuroanatomical mapping. Second, methods are introduced to improve understanding of the underlying principles of organization. Third, by combining existing knowledge from lower levels of organization, models can be used to make testable predictions about a higher-level organization where knowledge is absent or poor. This latter approach is useful for examining statistical properties of specific network connectivity when current experimental methods have not yet been able to fully reconstruct whole circuits of more than a few hundred neurons.

Using Eye Movements As An Experimental Probe Of Brain Function

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Author: R. John Leigh
Publisher: Elsevier
ISBN: 9780080932323
Size: 47.49 MB
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Using Eye Movements As An Experimental Probe Of Brain Function by R. John Leigh

Original Title: Using Eye Movements As An Experimental Probe Of Brain Function

This volume of Progress in Brain Research is based on the proceedings of a conference, "Using Eye Movements as an Experimental Probe of Brain Function," held at the Charing Cross Hospital Campus of Imperial College London, UK on 5th -6th December, 2007 to honor Professor Jean Büttner-Ennever. With 87 contributions from international experts – both basic scientists and clinicians – the volume provides many examples of how eye movements can be used to address a broad range of research questions. Section 1 focuses on extraocular muscle, highlighting new concepts of proprioceptive control that involve even the cerebral cortex. Section 2 comprises structural, physiological, pharmacological, and computational aspects of brainstem mechanisms, and illustrates implications for disorders as diverse as opsoclonus, and congenital scoliosis with gaze palsy. Section 3 addresses how the cerebellum transforms neural signals into motor commands, and how disease of such mechanisms may lead to ataxia and disorders such as oculopalatal tremor. Section 4 deals with sensory-motor processing of visual, vestibular, somatosensory, and auditory inputs, such as are required for navigation, and gait. Section 5 illustrates how eye movements, used in conjunction with single-unit electrophysiology, functional imaging, transcranial magnetic stimulation, and lesion studies have illuminated cognitive processes, including memory, prediction, and even free will. Section 6 includes 18 papers dealing with disorders ranging from congenital to acquired forms of nystagmus, genetic and degenerative neurological disorders, and treatments for nystagmus and motion sickness. * Clinicians will find important new information on the substrate for spinocerebellar ataxia, late-onset Tay-Sachs disease, Huntington disease, and pulvinar lesions * Organizes multiple articles on such topics as proprioception, short and longer-term memory, and hereditary cerebellar ataxias for a more coherent presentation * Articles on anatomic tracers, functional imaging, and computational neuroscience are illustrated in color

Tinnitus Pathophysiology And Treatment

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Author: Aage R. Moller
Publisher: Elsevier
ISBN: 9780080554464
Size: 20.52 MB
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Tinnitus Pathophysiology And Treatment by Aage R. Moller

Original Title: Tinnitus Pathophysiology And Treatment

Understanding tinnitus and treating patients with tinnitus must involve many disciplines of basic science and clinical practice. The book provides comprehensive coverage of a wide range of topics related to tinnitus including its pathophysiology, etiology and treatment. The chapters are written by researchers and clinicians who are active in the areas of basic science such as neurophysiology and neuroanatomy and in clinical specialties of psychology, psychiatry, audiology and otolaryngology. * Comprehensive coverage of the pathology and cause of tinnitus including genetics * Hyperacusis, phonophobia and other abnormalities in perception of sounds * The role of neural plasticity in tinnitus

Advances In Vasopressin And Oxytocin From Genes To Behaviour To Disease

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Author: Rainer Landgraf
Publisher: Elsevier
ISBN: 9780080932477
Size: 75.45 MB
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Advances In Vasopressin And Oxytocin From Genes To Behaviour To Disease by Rainer Landgraf

Original Title: Advances In Vasopressin And Oxytocin From Genes To Behaviour To Disease

Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohypophysial system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters. Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike. • Comprehensive review of OXT and AVP physiology and behaviour • Each chapter covers a novel aspect of OXT and AVP research and is written by a leading expert • Review articles are ideal for experts and newcomers to the field alike • Discusses fascinating behavioural effects of oxytocin and vasopressin • Summarizes the recent explosion of neuropeptide research, physiology and behaviour, is in one location

Serotonin Dopamine Interaction Experimental Evidence And Therapeutic Relevance

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Author: Giuseppe Di Giovanni
Publisher: Elsevier
ISBN: 9780080932682
Size: 57.24 MB
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Serotonin Dopamine Interaction Experimental Evidence And Therapeutic Relevance by Giuseppe Di Giovanni

Original Title: Serotonin Dopamine Interaction Experimental Evidence And Therapeutic Relevance

This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson’s disease. This extremely important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently active areas of dopamine/serotonin interactions. * Provides an understanding of the interaction between Serotonin and Dopamine. * Appeals equally to specialists, general practitioners, students and researchers. * Contributes to the debate on new pharmacological approaches to several psychopathological states * Gives a comprehensive anatomical description plus the physiology and pharmacology of dopaminergic and serotonergic systems * Singles out neuropsychiatric and suggests new therapeutic approaches.


Download Read Online Glaucoma book
Author: Carlo Nucci
Publisher: Newnes
ISBN: 0444532560
Size: 47.67 MB
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Glaucoma by Carlo Nucci

Original Title: Glaucoma

Glaucoma is one of the main causes of blindness throughout the world. It is characterized by death of the retinal ganglion cells, which is associated with loss of the axons making up the optic nerve. Recent studies have demonstrated support for the classification of glaucoma as a degenerative disease of the central nervous system (CNS). The search for treatment modalities that are effective for all patients with glaucoma has resulted in numerous studies aimed at identifying neuroprotection strategies for the treatment of this disease, like those used for other degenerative diseases of the CNS. The present book will provide an in-depth examination of the most recent findings regarding glaucoma, including risk factors, diagnosis, clinical monitoring, treatment, and above all, the need for treatment based on the concept of neuroprotection. A large part of the book is devoted to research related to this new approach to the treatment of glaucoma. Aspects that will be analyzed include experimental models of glaucoma, clinical protocols for the study of neuroprotective therapies, mechanisms underlying glaucomatous damage to neurons of the retina and other “stations? in the visual pathways of the CNS, and finally proposals for new strategies for preventing neuronal injury in glaucoma patients. * Describes the most recent developments on neuroprotection of the optic nerve, including experimental models now used and clinical protocols * Discusses new strategies for the prevention of neuronal injury in glaucoma patients * Focuses on evidence-based risk factors, innovative diagnostic aspects and advanced medical/surgical treatment of glaucoma


Download Read Online Neuroendocrinology book
Publisher: Elsevier
ISBN: 9780444537034
Size: 60.59 MB
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Neuroendocrinology by

Original Title: Neuroendocrinology

Neuroendocrinology is a discipline which originated about 50 years ago as a branch of Endocrinology and that is now strictly linked to neuroscience. Volumes 181 and 182 of Progress in Brain Research provide a rapid view of the major points presently discussed at biological and clinical levels. The chapters have been written by top scientists who are directly involved in basic or clinical research and who use the most sophisticated biotechnological techniques. The volumes cover of the role of genetics in many endocrine-related events, like neuroendocrinological diseases and endocrine depenedent cancers (prostate, breast, etc,). Interesting information is also provided on possibile treatments of neurodegenerative brain diseases (e.g., Alzheimer and similar syndromes). • The best researchers in the field provide their conclusions in the context of the latest experimental results • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered • Of great value for researchers and experts, but also for students as a background reference


Download Read Online Attention book
Author: Narayanan Srinivasan
Publisher: Elsevier
ISBN: 0080959032
Size: 60.33 MB
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Attention by Narayanan Srinivasan

Original Title: Attention

This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume explores interdisciplinary research on Attention and interaction of Attention with other cognitive processes including perception, learning, and memory. The papers cover major research on attention in Cognitive Neuroscience and Cognitive Psychology. The volume presents recent advances on attention including binding, dynamics of attention, attention and perceptual organization, attention and consciousness, emotion and attention, development of attention, crossmodal attention, computational modeling of attention, control of actions, attention and memory, and meditation.

Mind And Motion The Bidirectional Link Between Thought And Action

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Author: Markus Raab
Publisher: Elsevier
ISBN: 9780080886145
Size: 10.82 MB
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Mind And Motion The Bidirectional Link Between Thought And Action by Markus Raab

Original Title: Mind And Motion The Bidirectional Link Between Thought And Action

This volume investigates the implications of how our brain directs our movements on decision making. An extensive body of knowledge in chapters from international experts is presented as well as integrative group reports discussing new directions for future research. The understanding of how people make decisions is of central interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. For the first time the current volume provides a multidisciplinary overview of how action and cognition are integrated in the planning of and decisions about action. * Offers intense, focused, and genuine interdisciplinary perspective * Conveys state-of-the-art and outlines future research directions on the hot topic of mind and motion (or embodied cognition) * Includes contributions from psychologists, neuroscientists, movement scientists, economists, and others

Cultural Neuroscience Cultural Influences On Brain Function

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Author: Juan Y. Chiao
Publisher: Elsevier
ISBN: 0080952216
Size: 25.35 MB
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Cultural Neuroscience Cultural Influences On Brain Function by Juan Y. Chiao

Original Title: Cultural Neuroscience Cultural Influences On Brain Function

This volume presents recent empirical advances using neuroscience techniques to investigate how culture influences neural processes underlying a wide range of human abilities, from perception and scene processing to memory and social cognition. It also highlights the theoretical and methodological issues with conducting cultural neuroscience research. Section I provides diverse theoretical perspectives on how culture and biology interact are represented. Sections II –VI is to demonstrate how cultural values, beliefs, practices and experience affect neural systems underlying a wide range of human behavior from perception and cognition to emotion, social cognition and decision-making. The final section presents arguments for integrating the study of culture and the human brain by providing an explicit articulation of how the study of culture can inform the study of the brain and vice versa.

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