Fundamental Bacterial Genetics

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Author: Nancy Trun
Publisher: John Wiley & Sons
ISBN: 1444311557
Size: 27.71 MB
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Fundamental Bacterial Genetics by Nancy Trun

Original Title: Fundamental Bacterial Genetics

Fundamental Bacterial Genetics presents a concise introduction to microbial genetics. The text focuses on one bacterial species, Escherichia coli, but draws examples from other microbial systems at appropriate points to support the fundamental concepts of molecular genetics. A solid balance of concepts, techniques and applications makes this book an accessible, essential introduction to the theory and practice of fundamental microbial genetics. FYI boxes - feature key experiments that lead to what we now know, biographies of key scientists, comparisons with other species and more. Study questions - at the end of each chapter, review and test students' knowledge of key chapter concepts. Key references - included both at chapter end and in a full reference list at the end of the book. Full Chapter on Genomics, Bioinformatics and Proteomics - includes coverage of functional genomics and microarrays. Dedicated website – animations, study resources, web research questions and illustrations downloadable for powerpoint files provide students and instructors with an enhanced, interactive experience.

Genetics Of Bacteria

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Author: Sheela Srivastava
Publisher: Springer Science & Business Media
ISBN: 8132210905
Size: 78.29 MB
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Genetics Of Bacteria by Sheela Srivastava

Original Title: Genetics Of Bacteria

Described as the earliest, simplest life forms, with unlimited metabolic versatility, bacteria are ideally suited to answer some very fundamental questions on life and its processes. They have been employed in almost all fields of biological studies, including Genetics. The whole edifice of science of Genetics centers around three processes: the generation, expression, and transmission of biological variation, and bacteria offer immediate advantages in studying all the three aspects of heredity. Being haploid and structurally simple, it becomes easy to isolate mutations of various kinds and relate them to a function. The availability of such mutants and their detailed genetic and biochemical analyses lead to a gamut of information on gene expression and its regulation. While studying the transmission of biological variation, it is clear that unlike their eukaryotic counterpart, a more genetic approach needs to be employed. Transmission of genetic information in most eukaryotic organisms rests on sexual reproduction that allows the generation of genetically variable offspring through the process of gene recombination. Even though bacteria show an apparent preference for asexual reproduction, they too have evolved mechanisms to trade their genetic material. In fact, bacteria not only could acquire many genes from close relatives, but also from entirely distant members through the process of horizontal gene transfer. Their success story of long evolutionary existence will stand testimony to these mechanisms. While teaching a course on Microbial Genetics to the post-graduate students at Delhi University, it was realized that a book devoted to bacterial genetics may be very handy to the students, researchers, and teachers alike. A strong foundation in genetics also helps in comprehending more modern concepts of molecular biology and recombinant DNA technology, always a favorite with the students and researchers. Planning the format of the book, emphasis has been laid on the generation and transmission of biological variability. The omission of expression part is indeed intentional because lots of information is available on this aspect in any modern biology book. The contents are spread over seven chapters and the text is supported with figures/tables wherever possible. The endeavor has been to induce the readers to appreciate the strength of bacterial genetics and realize the contribution of these tiny organisms to the growth of biological sciences as a whole and genetics in particular.

Veterinary Microbiology And Microbial Disease

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Author: P. J. Quinn
Publisher: John Wiley & Sons
ISBN: 1118251164
Size: 24.48 MB
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Veterinary Microbiology And Microbial Disease by P. J. Quinn

Original Title: Veterinary Microbiology And Microbial Disease

Microbiology is one of the core subjects for veterinary students, and since its first publication in 2002, Veterinary Microbiology and Microbial Disease has become an essential text for students of veterinary medicine. Fully revised and expanded, this new edition updates the subject for pre-clinical and clinical veterinary students in a comprehensive manner. Individual sections deal with bacteriology, mycology and virology. Written by an academic team with many years of teaching experience, the book provides concise descriptions of groups of microorganisms and the diseases which they cause. Microbial pathogens are discussed in separate chapters which provide information on the more important features of each microorganism and its role in the pathogenesis of diseases of animals. The international and public health significance of these pathogens are reviewed comprehensively. The final section is concerned with the host and is organized according to the body system affected. Tables, boxes and flow diagrams provide information in an easily assimilated format. This edition contains new chapters on molecular diagnostics and on infectious conditions of the skin, cardiovascular system, urinary tract and musculoskeletal system. Many new colour diagrams are incorporated into this edition and each chapter has been updated. Key features of this edition: Twelve new chapters included Numerous new illustrations Each chapter has been updated Completely re-designed in full colour Fulfils the needs of veterinary students and academics in veterinary microbiology Companion website with figures from the book as Powerpoints for viewing or downloading by chapter: Veterinary Microbiology and Microbial Disease remains indispensable for all those studying and teaching this essential component of the veterinary curriculum.

Microbial Genetics Applied To Biotechnology

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Author: Venetia A. Saunders
Publisher: Springer Science & Business Media
ISBN: 146159796X
Size: 71.34 MB
Format: PDF, ePub, Mobi
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Microbial Genetics Applied To Biotechnology by Venetia A. Saunders

Original Title: Microbial Genetics Applied To Biotechnology

This book describes techniques of microbial genetics and how they may be applied to biotechnology. The text is concerned largely with the application of these techniques to microbial technology. We have therefore utilised illustrative material that is given in our own courses in applied micro biology. The book assumes in the reader a basic knowledge of microbial will prove useful to under genetics and industrial microbiology. We hope it graduates, postgraduates and others taking courses in applied micro biology. We would like to thank various colleagues, including John Carter, Julian Davies, Gordon Dougan, David Hopwood, Gwyn Humphreys, Alan McCarthy, David O'Connor, Tony Hart, Steve Oliver, Roger Pickup, Hilary Richards, Bob Rowlands, David Sherratt, Peter Strike, Richard Sykes and Liz Wellington, all of whom provided information at various stages during the writing of this book. Many thanks are also due to Linda Marsh for patiently typing the many drafts of the manuscript. 1 Introduction Natural genetic variation has always been exploited by man to improve the properties of microbial strains. Spontaneous mutations that arise in micro bial populations and that have properties advantageous to man have been gradually selected over centuries of use. However, it is only since the development of modem genetic techniques that more rational approaches have been possible. Such newer technologies have permitted the tailoring of microorganisms, plant or animal cells to manufacture specific products of commercial or social benefit and to manage the environment.

Bacterial Conjugation

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Author: D.B. Clewell
Publisher: Springer
Size: 58.23 MB
Format: PDF
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Bacterial Conjugation by D.B. Clewell

Original Title: Bacterial Conjugation

Bacterial plasmids originating in a wide range of genera are being studied from a variety of perspectives in hundreds of laboratories around the globe. These elements are well known for carrying "special" genes that confer important survival properties, frequently neces sary under atypical conditions. Classic examples of plasmid-borne genes are those provid ing bacterial resistance to toxic substances such as antibiotics, metal ions, and bacte riophage. Often included are those determining bacteriocins, which may give the bacterium an advantage in a highly competitive environment. Genes offering metabolic alternatives to the cell under nutritionally stressed conditions are also commonly found on plasmids, as are determinants important to colonization and pathogenesis. It is likely that in many, if not most, cases plasmids and their passenger determinants represent DNA acquired recently by their bacterial hosts, and it is the characteristic mobility of these elements that enables their efficient establishment in new bacterial cells by the process known as conjugation. Whereas many plasmids are fully capable of promoting their own conjugal transfer, others move only with help from coresident elements. The ability of a plasmid to establish itself in a variety of different species is com mon, and recent studies have shown that transfer can in some cases occur from bacterial cells to eukaryotes such as yeast.

Biomedical Institutions Biomedical Funding And Public Policy

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Author: H. Hugh Fudenberg
Publisher: Springer Science & Business Media
ISBN: 1468444484
Size: 44.61 MB
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Biomedical Institutions Biomedical Funding And Public Policy by H. Hugh Fudenberg

Original Title: Biomedical Institutions Biomedical Funding And Public Policy

The world is on the threshold of a great new industrial revolution, a 1 scientific-industrial revolution. Recombinant DNA technology and hybridoma technology ("monoclonal antibodies") have already pro vided unique investment opportunities for venture capitalists. Hence published reports of biomedical research are no longer restricted to scientific journals, but now appear regularly not only in weekly news 2 magazines like Time and U. S. News & World Report,3 but also in the financial sections of The New York Times,4 The Wall Street Journal,S 6 8 Business Week, Fortune,7 and The Economist, as well as in such stock 9 market advisory publications as New Issues and Inc. (The Magazine for Growing Companies). 10 These publications now appear to be as impor tant to biomedical scientists in keeping abreast of new scientific devel opments in biotechnology as is Current Contents. (The costs of health cost provision and of fundamental biomedical research are now also being followed by such media. ) Conversely, Wall Street financial bro kers increasingly no longer confine their reading to economic journals but are also perusing Nature,ll Science,12 and Science N 13 for infor ews mation on both fiscal and scientific advances in these areas. It is obvious that the information explosion in biotechnology is crossing traditional boundaries (e. g. , ref. 14). This volume is the second of several that are intended to inform both the biomedical community and interested intelligent laymen of the political and economic implications of biomedical research.

Advanced Bacterial Genetics Use Of Transposons And Phage For Genomic Engineering

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Publisher: Elsevier
ISBN: 9780080475103
Size: 63.95 MB
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Advanced Bacterial Genetics Use Of Transposons And Phage For Genomic Engineering by

Original Title: Advanced Bacterial Genetics Use Of Transposons And Phage For Genomic Engineering

The critically acclaimed laboratory standard for more than fifty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. This new volume presents methods related to the use of bacterial genetics for genomic engineering. The book includes sections on strain collections and genetic nomenclature; transposons; and phage.

Jawetz Melnick Adelberg S Medical Microbiology

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Publisher: McGraw-Hill
ISBN: 9780071476669
Size: 23.93 MB
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Jawetz Melnick Adelberg S Medical Microbiology by

Original Title: Jawetz Melnick Adelberg S Medical Microbiology

Job: Brooks et al: Jawetz, Melnick & Adelberg's Medical Microbiology, 24e back cover copy 0071476660 9780071476669 [title Jawetz, Melnick & Adelberg's Medical Microbiology Twenty-fourth Edition [authors] Geo. F. Brooks, MD Karen C. Carroll, MD Janet S. Butel, PhD Stephen A. Morse, Ph.D. [bar/burst 200] USMLE-format questions [headline The landmark clinical guide to the role microorganisms play in human health and illnesses -extensively revised and updated Linking fundamental microbiology concepts with the diagnosis and treatment of clinical infections, this one-of-a-kind, portable text delivers an essential overview of the organisms and agents involved in clinical microbiology. In addition to brief descriptions of the organisms, you'll find vital perspectives on pathogenesis, diagnostic laboratory tests, clinical findings, treatment, and epidemiology. The book's purpose is to introduce basic clinical microbiology through the fields of bacteriology, virology, mycology, and parasitology giving you a far-reaching, yet accessible review of the discipline that you can't find anywhere else. Supporting this acclaimed coverage are more than 300 informative illustrations and tables, each designed to clarify and drive home important chapter concepts. New to this Edition: Updates to critical topics throughout, particularly in the areas of hepatitis viruses, the HIV virus, and bacterial virulence factors Refreshed USMLE questions Revised list of microorganisms and viruses featured on the inside of the book's covers [ [McGraw-Hill Medical logo]

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