Gerd

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Author: Parakrama T. Chandrasoma
Publisher: Academic Press
ISBN: 0128098562
Size: 70.34 MB
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Gerd by Parakrama T. Chandrasoma


Original Title: Gerd

GERD: A New Understanding of Pathology, Pathophysiology, and Treatment transforms the assessment of gastroesophageal reflux disease (GERD) from its present state, which is largely dependent on clinical definition and management, to a more objective scientific basis that depends on pathologic assessment. Sequential chapters in this single-author book describe the fetal development of the esophagus, the normal adult state, and the way exposure to gastric juice causes epithelial and lower esophageal sphincter damage at a cellular level. It allows recognition of the pathologic manifestations of lower esophageal sphincter damage and develops new histopathologic criteria for quantitating such damage. This understanding provides new pathologic criteria for definition and diagnosis of GERD from its earliest cellular stage. Algorithms based on measurement of sphincter damage can identify, even before the onset of clinical GERD, persons who will never develop GERD during life, those who develop GERD but remain with mild and easily controlled disease, and those who will progress to severe GERD with failure to control symptoms, Barrett esophagus and adenocarcinoma. Aggressive early intervention in the last group with the objective of preventing disease progression to its end points of uncontrolled symptoms and adenocarcinoma becomes feasible. Provides a new method of assessment of GERD that has never previously been presented, creating a pathway to control. Describes a new pathologic test based on standard histology that can define lower esophageal sphincter damage. Sequential chapters outline the way GERD progresses from the perspective of the amount of damage to the lower esophageal sphincter. Provides new avenues of clinical research and technologic innovations in pathology and treatment aimed at preventing esophageal adenocarcinoma.

Laparoscopic Surgery

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Author: Ronald C. Merrell
Publisher: Springer Science & Business Media
ISBN: 1461214084
Size: 19.48 MB
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Laparoscopic Surgery by Ronald C. Merrell


Original Title: Laparoscopic Surgery

In May 1997 the Faculty of Surgery from the University of Athens and elsewhere gathered with colleagues in Athens for the third time in 6 years to continue our discussions on the progress, problems, realization, and future of laproscopic surgery. The topics were rather inclusive with regard to the issues that defined the field, and the assembled investigators, educa tors, and clinicians brought a rich experience and clear vision of the field in the coming years. The decision had been made months before to collect our thoughts and experience as a colloquium of the state of laproscopic surgery in the tenth year following the report of Mouret on laparoscopic cholecy stectomy, not as the proceedings of the specific meeting. At the end of a decade of mercurial advance, heated debate, professional turmoil, and very little science, it was clear that general surgery would never be the same. Laproscopic surgery is now fully established and requires accommodation in the curriculum, practice, and research of surgery for the foreseeable future. This book is called a colloquium on laparoscopy because it collects the thoughts of many workers in the form of consensus presentations. It is offered to any surgeon who is ready to survey this field with clear eyes, absent of emotion or hyperbole, in our evolution of a better standard of care for surgical patients.

Advancing Medicine With Food And Nutrients Second Edition

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Author: Ingrid Kohlstadt
Publisher: CRC Press
ISBN: 1439887721
Size: 19.77 MB
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Advancing Medicine With Food And Nutrients Second Edition by Ingrid Kohlstadt


Original Title: Advancing Medicine With Food And Nutrients Second Edition

Food and nutrients are the original medicine and the shoulders on which modern medicine stands. But in recent decades, food and medicine have taken divergent paths and the natural healing properties of food have been diminished in the wake of modern technical progress. With contributions from highly regarded experts who work on the frontlines of disease management, the bestselling first edition of Advancing Medicine with Food and Nutrients, Food and Nutrients in Disease Management effectively brought food back into the clinical arena, helping physicians put food and nutrients back on the prescription pad. Board-certified in General Preventive Medicine, Ingrid Kohlstadt, MD, MPH has been elected a Fellow of the American College of Nutrition and a Fellow of the American College of Preventive Medicine. Guided by Dr. Kohlstadt, this authoritative reference equips clinicians with the information they need to fully utilize nutritional medicine in their practice. New in the Second Edition Toxic exposures such as molds, microbial infections, xenoestrogens, heavy metals, and inert nanoparticles Food safety issues: precautions for patients with preexisting medical conditions, adequate labeling of food allergens such as gluten, potential adverse effects of artificial sweeteners, consequences of applying ionizing radiation to food, food-borne mycotoxins, critical food restrictions following bariatric surgery, precautions for preparing food in the home Consumer advocacy issues on navigating claims of medical foods and dietary supplements Physical forces on nutritional needs, such as ultraviolet light initiating vitamin D synthesis, non-ionizing radiation’s effects on brain glucose metabolism and excess body fat’s effects on inflammation and hydration Preventive medicine and how to preserve resiliency at the individual and public health levels Written by doctors for doctors, Advancing Medicine with Food and Nutrients, Second Edition reunites food and medicine. Buttressed with new evidence, leading physicians on the frontlines of disease management apply the latest scientific advances to the clinical practice of medicine. Each chapter offers adjuncts to standard care, fewer side effects, improved risk reduction, or added quality of life. An article by Ingrid Kohlstadt on education and nutrition appeared in TIME Magazine online on November 12, 2014.

Diagnostic Atlas Of Gastroesophageal Reflux Disease

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Author: Parakrama T. Chandrasoma
Publisher: Academic Press
ISBN: 9780080878034
Size: 59.14 MB
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Diagnostic Atlas Of Gastroesophageal Reflux Disease by Parakrama T. Chandrasoma


Original Title: Diagnostic Atlas Of Gastroesophageal Reflux Disease

Gastroesophageal reflux is one of the most common maladies of mankind. Approximately 40% of the adult population of the USA suffers from significant heartburn and the numerous antacids advertised incessantly on national television represents a $8 billion per year drug market. The ability to control acid secretion with the increasingly effective acid-suppressive agents such as the H2 blockers (pepcid, zantac) and proton pump inhibitors (nexium, prevacid) has given physicians an excellent method of treating the symptoms of acid reflux. Unfortunately, this has not eradicated reflux disease. It has just changed its nature. While heartburn, ulceration and strictures have become rare, reflux-induced adenocarcinoma of the esophagus is becoming increasingly common. Adenocarcinoma of the esophagus and gastric cardia is now the most rapidly increasing cancer type in the Western world. At present, there is no histologic test that has any practical value in the diagnosis of reflux disease. The only histologic diagnostic criteria are related to changes in the squamous epithelium which are too insensitive and nonspecific for effective patient management. It is widely recognized that columnar metaplasia of the esophagus (manifest histologically as cardiac, oxyntocardiac and intestinal epithelia) is caused by reflux. However, except for intestinal metaplasia, which is diagnostic for Barrett esophagus, these columnar epithelia are not used to diagnose reflux disease in biopsies. The reason for this is that these epithelial types are indistinguishable from "normal" "gastric" cardiac mucosa. In standard histology texts, this "normal gastric cardia" is 2-3 cm long. In the mid-1990s, Dr. Chandrasoma and his team at USC produced autopsy data suggesting that cardiac and oxyntocardiac mucosa is normally absent from this region and that their presence in biopsies was histologic evidence of reflux disease. From this data, they determined that the presence of cardiac mucosa was a pathologic entity caused by reflux and could therefore be used as a highly specific and sensitive diagnostic criterion for the histologic diagnosis of reflux disease. They call this entity "reflux carditis". In addition, the length of these metaplastic columnar epithelia in the esophagus was an accurate measure of the severity of reflux disease in a given patient. At present, there is some controversy over whether cardiac mucosa is totally absent or present normally to the extent of 0-4 mm. While this should not be a deterrent to changing criteria which are dependent on there normally being 20-30 cm of cardiac mucosa, there has been little mainstream attempt to change existing endoscopic and pathologic diagnostic criteria in the mainstream of either gastroenterology or pathology. The ATLAS will be the source of easily digestible practical information for pathologists faced with biopsies from this region. It will also guide gastroenterologists as they biopsy these patients. The American Gastroenterological Association claims there are 14,500 members worldwide who are practicing physicians and scientists who research, diagnose and treat disorders of the gastrointestinal tract and liver According to the American Society for Clinical Pathology, there are 12,000 board certified pathologists in the U.S. Adenocarcinoma of the esophagus and gastric cardia is now the most rapidly increasing cancer type in the Western world Approximately 40% of the adult population of the U.S. suffers from significant heartburn and the numerous antacids advertised on national television represents an $8 billion per year drug market

Shackelford S Surgery Of The Alimentary Tract

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Author: Charles J. Yeo
Publisher: Elsevier Health Sciences
ISBN: 1455738077
Size: 74.26 MB
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Shackelford S Surgery Of The Alimentary Tract by Charles J. Yeo


Original Title: Shackelford S Surgery Of The Alimentary Tract

Comprehensive and complete, Shackelford’s Surgery of the Alimentary Tract delivers the definitive, clinically oriented, cutting-edge guidance you need to achieve optimal outcomes managing the entire spectrum of gastrointestinal disorders. Make effective use of the latest endoscopic, robotic, and minimally invasive procedures as well as medical therapies with unbeatable advice from a "who’s who" of international authorities! Find expert answers to any clinical question in gastrointestinal surgery, from the esophagus to the colon. See exactly what to look for and how to proceed from an abundance of beautifully detailed intraoperative and laparoscopic photographs.

Eosinophilic Esophagitis An Issue Of Gastroenterology Clinics Of North America

Download Read Online Eosinophilic Esophagitis An Issue Of Gastroenterology Clinics Of North America  book
Author: Ikuo Hirano
Publisher: Elsevier Health Sciences
ISBN: 0323299393
Size: 72.80 MB
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Eosinophilic Esophagitis An Issue Of Gastroenterology Clinics Of North America by Ikuo Hirano


Original Title: Eosinophilic Esophagitis An Issue Of Gastroenterology Clinics Of North America

Ikuo Hirano, an international leader and pioneer in EoE, has assembled well-recognized experts in the field to provide a state-of-the-art, practical understanding of EoE for both children and adults in 2014. Topics you will find in this issue of Gastroenterology Clinics of North America include the epidemiology, clinical presentation, diagnosis, and management of EoE as well as a glimpse into what the future holds. In addition, articles dedicated to mechanisms of disease pathogenesis and complications complete this comprehensive assessment of the field at present.The Editors believe that this issue will enhance your understanding of EoE.

Head And Neck Pathology With Clinical Correlations

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Author: Yao S. Fu
Publisher:
ISBN:
Size: 56.96 MB
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Head And Neck Pathology With Clinical Correlations by Yao S. Fu


Original Title: Head And Neck Pathology With Clinical Correlations

This groundbreaking resource examines the full range of head and neck diseases integrating both pathologic and clinical information for neoplastic as well as non-neoplastic entities. All aspects of pathologic issues are discussedfrom diagnosis to the pathologic parameters that have an impact on patient management. Section One covers general principles, including cellular and molecular biology, epidemiology, ethics, HIV and AIDS, and fine needle aspiration biopsies. Then, Section Two discusses diseases by anatomic sitefrom the nasal cavity and paranasal sinuses...through the thyroid and parathyroid...to the ear and temporal lobe and neck. Presents in-depth discussions of pathology with clinical correlationsenabling readers to improve diagnostic accuracy and understand the clinical problems associated with each diagnosis Includes in-depth coverage of gross and microscopic findings, the use of ultrastructural and immunohistochemical techniques in diagnosis and differential diagnosis Offers comprehensive coverage of surgical anatomy, physiology, diagnostic techniques, as well as clinical management Provides guidance on the handling and reporting of resected specimens Features over 1495 illustrations1000 in full colorthat aid in diagnosis Includes an outline at the beginning of each chapter to make information easy to find

Sleisenger And Fordtran S Gastrointestinal And Liver Disease

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Author: Mark Feldman
Publisher: Elsevier Health Sciences
ISBN: 1437727670
Size: 55.53 MB
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Sleisenger And Fordtran S Gastrointestinal And Liver Disease by Mark Feldman


Original Title: Sleisenger And Fordtran S Gastrointestinal And Liver Disease

Make optimal use of the newest techniques, technologies, and treatments with Sleisenger and Fordtran's Gastrointestinal and Liver Disease - the indispensable information source in this broad field! Edited by Mark Feldman, MD, Lawrence S. Friedman, MD, and Lawrence J. Brandt, MD, this 9th Edition equips you with the amassed knowledge of hundreds of respected authorities from around the world, helping you to overcome all of your most complex clinical challenges and make the most effective use of the newest techniques, technologies, and treatments. Significant updates on bariatric surgery, Barrett's esophagus, and many other evolving areas keep your practice current. Full-text online access includes downloadable illustrations and links to reference abstracts. The result remains the indispensable core reference in gastroenterology and hepatology. World-renowned experts provide reliable guidance on every area of your field. A consistent, full-color chapter design lets you find information quickly. Significant updates on bariatric surgery, Barrett's esophagus, endoscopic ultrasound, endosonography, treatment of liver disease, and much more keep you current on the latest advances. Many new contributors from all over the world provide you with fresh insights on all areas of gastroenterology and hepatology. Full-text online access via Expert Consult includes downloadable illustrations and links to reference abstracts.

Diagnostic Pathology

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Author: Joel K. Greenson
Publisher: Lippincott Williams & Wilkins
ISBN:
Size: 30.77 MB
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Diagnostic Pathology by Joel K. Greenson


Original Title: Diagnostic Pathology

Designed as an easy-to-use and comprehensive reference for practicing pathologists, Diagnostic Pathology: Gastrointestinal is the highly anticipated first volume in the Diagnostic Pathology series offered by Amirsys. As readers have come to expect from Amirsys reference tools, Diagnostic Pathology: Gastrointestinal is filled with over 1,500 superior medical images, including gross pathology, a wide range of pathology stains, and detailed medical illustrations. Readers will also find a variety of quick-reference test data tables, one of the most useful hallmarks of the series. This handsome volume covers over 200 diagnoses and is a veritable one-stop shop for any gastrointestinal pathology reference need.

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