Gnotobiotics

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Author: Trenton R Schoeb
Publisher: Academic Press
ISBN: 0128045833
Size: 64.77 MB
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Gnotobiotics by Trenton R Schoeb


Original Title: Gnotobiotics

Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal species Analyzes microbiota in numerous contexts Presents detailed coverage of the protocols and operation of a gnotobiotic facility

Proceedings Of The Gnotobiotic Symposium And Workshop June 15 And 16 Michigan State University East Lansing

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Author: Association of Applied Gnotobiotics, College of Veterinary Medicine, Continuing Education Service
Publisher:
ISBN:
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Proceedings Of The Gnotobiotic Symposium And Workshop June 15 And 16 Michigan State University East Lansing by Association of Applied Gnotobiotics, College of Veterinary Medicine, Continuing Education Service


Original Title: Proceedings Of The Gnotobiotic Symposium And Workshop June 15 And 16 Michigan State University East Lansing


The Mouse In Biomedical Research

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Author:
Publisher: Elsevier
ISBN: 9780080469072
Size: 46.81 MB
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The Mouse In Biomedical Research by


Original Title: The Mouse In Biomedical Research

Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse’s normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Germfree And Gnotobiotic Animal Models

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Author: Bernard S. Wostmann
Publisher: CRC Press
ISBN: 9780849340086
Size: 70.29 MB
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Germfree And Gnotobiotic Animal Models by Bernard S. Wostmann


Original Title: Germfree And Gnotobiotic Animal Models

The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. The need for such an animal model for use in biomedical studies was first expressed by Pasteur in the late 1800s. Subsequent development of germfree and gnotobiotic animals led to an explosion of studies on the effects of microflora and its components on the physiology and metabolism of the host. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.

Gnotobiotic Mouse Technology

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Author: Chriss J. Vowles
Publisher: CRC Press
ISBN: 1498736335
Size: 72.50 MB
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Gnotobiotic Mouse Technology by Chriss J. Vowles


Original Title: Gnotobiotic Mouse Technology

The popularity of germ-free animal models, particularly mice, for investigation of human physiology and disease has recently exploded. Gnotobiotic Mouse Technology: An Illustrated Guide provides the first manual for the maintenance, husbandry, and experimental manipulation of germ-free and gnotobiotic mice. It includes information on all aspects of establishing and operating a germ-free mouse research facility, from basic principles and equipment to detailed instructions for assembling and maintaining isolators, sterilizing supplies, handling animals, and monitoring sterility. The book breaks down techniques and procedures into modules, each of which contains a step-by-step practical and visual guide to a set of related procedures. Each description consists of a materials list, introduction, and general overview, followed by a thoroughly illustrated walkthrough of the steps for each procedure. The descriptions end with troubleshooting tips. Technical chapters are heavily illustrated and include notations of potential pitfalls and alternatives. Other chapters discuss management procedures and practices such as the hiring and training of personnel, setting fee schedules, and record keeping. This book is a landmark resource for establishing and maintaining a facility for germ-free mouse research. Useful to both technicians and investigators, it presents every step necessary to establish a successful facility. It also gives direction in expanding multi-user facilities and applying new technologies to your current practices.

The Mouse In Biomedical Research

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Author: Henry L. Foster
Publisher: Academic Press
ISBN: 1483262766
Size: 19.66 MB
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The Mouse In Biomedical Research by Henry L. Foster


Original Title: The Mouse In Biomedical Research

The Mouse in Biomedical Research, Volume III: Normative Biology, Immunology, and Husbandry focuses on the normative biology, immunology, and husbandry of laboratory mice. Topics covered range from gnotobiotics and gastrointestinal microflora to animal health surveillance and health delivery systems, along with environmental monitoring. The management and design of breeding and research facilities are also discussed. Comprised of 18 chapters, this volume begins with an overview of studies involving gnotobiotic mice, the induction of gnotobiosis, and microbiological testing of gnotobiotic animals. Maintenance of breeding colonies of gnotobiotic animals is also considered, together with the shipment of gnotobiotes and laboratory facilities for using gnotobiotes. The reader is then introduced to management and design of breeding and research facilities for gnotobiotic mice; practical factors associated with providing adequate nutrition for laboratory mice; and environmental and equipment monitoring. Subsequent chapters deal with the basic biology of the mouse, including anatomy, embryology, reproductive physiology, physiology, endocrinology, hematology, clinical biochemistry, and gastrointestinal microflora. The book also examines immunoglobulins and immunoglobulin genes; lymphocyte immunogenetics; immune response disorders; and biomethodology and surgical techniques. This monograph will be useful to biologists, immunologists, researchers, and others those who use mice in the laboratory or are concerned with the production and maintenance of colonies of mice.

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