Handbook Of Immunohistochemistry And In Situ Hybridization Of Human Carcinomas

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Author: M. A. Hayat
Publisher: Elsevier
ISBN: 0080456251
Size: 57.87 MB
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Handbook Of Immunohistochemistry And In Situ Hybridization Of Human Carcinomas by M. A. Hayat


Original Title: Handbook Of Immunohistochemistry And In Situ Hybridization Of Human Carcinomas

Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. * The only book available that translates molecular genetics into cancer diagnosis * The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations * Methods discussed were either developed or refined by expert contributors in their own laboratories

Cell Biology

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Author: Julio E. Celis
Publisher: Elsevier
ISBN: 0121647307
Size: 11.45 MB
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Cell Biology by Julio E. Celis


Original Title: Cell Biology

This four-volume laboratory manual contains comprehensive state-of-the-art protocols essential for research in the life sciences. Techniques are presented in a friendly step-by-step fashion, providing useful tips and potential pitfalls. The important steps and results are beautifully illustrated for further ease of use. This collection enables researchers at all stages of their careers to embark on basic biological problems using a variety of technologies and model systems. This thoroughly updated third edition contains 165 new articles in classical as well as rapidly emerging technologies. Topics covered include: * Cell and Tissue Culture: Associated Techniques, Viruses, Antibodies, Immunocytochemistry (Volume 1) * Organelle and Cellular Structures, Assays (Volume 2) * Imaging Techniques, Electron Microscopy, Scanning Probe and Scanning Electron Microscopy, Microdissection, Tissue Arrays, Cytogenetics and In Situ Hybridization, Genomics and Transgenic Knockouts and Knock-down Methods (Volume 3) * Transfer of Macromolecules, Expression Systems, Gene Expression Profiling (Volume 4) * Indispensable bench companion for every life science laboratory * Provides the latest information on the plethora of technologies needed to tackle complex biological problems * Includes numerous illustrations, some in full color, supporting steps and results

Tietz Textbook Of Clinical Chemistry And Molecular Diagnostics

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Author: Carl A. Burtis
Publisher: Elsevier Health Sciences
ISBN: 1455759422
Size: 73.72 MB
Format: PDF
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Tietz Textbook Of Clinical Chemistry And Molecular Diagnostics by Carl A. Burtis


Original Title: Tietz Textbook Of Clinical Chemistry And Molecular Diagnostics

As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including: analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and applications of statistical methods. In addition to updated content throughout, this two-color edition also features a new chapter on hemostasis and the latest advances in molecular diagnostics. Section on Molecular Diagnostics and Genetics contains nine expanded chapters that focus on emerging issues and techniques, written by experts in field, including Y.M. Dennis Lo, Rossa W.K. Chiu, Carl Wittwer, Noriko Kusukawa, Cindy Vnencak-Jones, Thomas Williams, Victor Weedn, Malek Kamoun, Howard Baum, Angela Caliendo, Aaron Bossler, Gwendolyn McMillin, and Kojo S.J. Elenitoba-Johnson. Highly-respected author team includes three editors who are well known in the clinical chemistry world. Reference values in the appendix give you one location for comparing and evaluating test results. NEW! Two-color design throughout highlights important features, illustrations, and content for a quick reference. NEW! Chapter on hemostasis provides you with all the information you need to accurately conduct this type of clinical testing. NEW! Six associate editors, Ann Gronowski, W. Greg Miller, Michael Oellerich, Francois Rousseau, Mitchell Scott, and Karl Voelkerding, lend even more expertise and insight to the reference. NEW! Reorganized chapters ensure that only the most current information is included.

Diagnostic Histopathology Of Tumors

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Author: Christopher D. M. Fletcher
Publisher: Elsevier Health Sciences
ISBN: 1455737542
Size: 63.86 MB
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Diagnostic Histopathology Of Tumors by Christopher D. M. Fletcher


Original Title: Diagnostic Histopathology Of Tumors

Diagnose tumors with confidence with Diagnostic Histopathology of Tumors, 4th Edition. Dr. Christopher Fletcher's renowned reference provides the advanced, expert guidance you need to evaluate and interpret even the most challenging histopathology specimens more quickly and accurately. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Diagnose efficiently and effectively using diagnostic flow charts, correlations of gross appearances to microscopic findings, and differential diagnosis tables for better recognition and evaluation of similar-looking entities. Employ immunohistochemistry, molecular and genetic diagnostic tests, and other modern techniques as well as the best morphologic diagnostic methods to effectively identify each tumor or tumor-like entity. Utilize new, clinically important molecular genetic data and updated classification schemes to help guide treatment and targeted therapy. Apply the latest techniques and diagnostic criteria with completely rewritten chapters on Small and Large Intestines, Heart, Larynx and Trachea, Ear, and Peritoneum. Find critical information quickly thanks to more tables and bulleted lists throughout.

Haschek And Rousseaux S Handbook Of Toxicologic Pathology

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Author: Wanda M. Haschek
Publisher: Elsevier
ISBN: 0080491448
Size: 66.59 MB
Format: PDF, Kindle
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Haschek And Rousseaux S Handbook Of Toxicologic Pathology by Wanda M. Haschek


Original Title: Haschek And Rousseaux S Handbook Of Toxicologic Pathology

A comprehensive understanding of toxicologic pathology is essential for those in industry, academia, and government who make decisions concerning the safety and efficacy of drugs and chemicals. Toxicologic pathology relies heavily on the fields of both toxicology and pathology, which are well covered individually in various texts and references; however, there are few texts that address the field of toxicologic pathology. The Handbook of Toxicologic Pathology fills this void and is thus essential for all health professionals within or interacting with the field of toxicologic pathology. This two-volume set provides the reader with a single reference for toxicologic pathology. In volume I, the book covers toxicologic pathology in its basic aspects, including its definition, the basic biochemical and morphologic mechanisms underlying the discipline, the basic practice of toxicologic pathology (including special techniques) and issues essential to the understanding of toxicologic pathology such as risk assessment, experimental design, and statistical analysis. Next, the book moves to specific issues affecting the "practice" toxicologic pathology, including issues such as knowledge management, regulatory affairs and writing pathology reports. Finally, Volume I closes with several chapters that deal with specific classes of environmental toxicants such as endocrine disruptors and heavy metals. Volume II addresses the toxicologic pathology in a thoroughly standardized systems manner, addressing the basic structure and function of a particular organ system, its response to toxic injury, mechanisms of injury and methods of evaluation of such injury. Key Features * Easy to find, up-to-date reference information * Graphic and photographic plates * Current hot topics and anticipated changes in toxicologic pathology * Standardized chapter format * Topics that are addressed in both a broad and deep manner, resulting in a stand alone text * Added coverage of important environmental toxicants * Chapters authored by internationally recognized experts and peer-reviewed

Comprehensive Cytopathology

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Author: Marluce Bibbo
Publisher: Elsevier Health Sciences
ISBN: 1437719627
Size: 28.72 MB
Format: PDF
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Comprehensive Cytopathology by Marluce Bibbo


Original Title: Comprehensive Cytopathology

This best-selling book provides you with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and covers the recognized normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is lavishly illustrated, making it the perfect practical resource for daily reference in the laboratory. Provides an accessible guide to diagnostic investigation and screening. Includes a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Utilizes a consistent chapter structure to make finding the answers you need quick and easy. Provides updates to crucial chapters to keep you on top of the latest diagnosis and techniques. Incorporates differential diagnosis tables for easy comparison/contrast of diagnoses. Offers more than 1800 full-color images depicting a full range of normal and abnormal findings. Discusses new concepts on molecular basis of neoplasia. Explores the role of cytogenetics in cancer development.

Translating Molecular Biomarkers Into Clinical Assays

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Author: Russell Weiner
Publisher: Springer
ISBN: 3319407937
Size: 46.42 MB
Format: PDF, ePub, Mobi
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Translating Molecular Biomarkers Into Clinical Assays by Russell Weiner


Original Title: Translating Molecular Biomarkers Into Clinical Assays

This handbook covers established and advanced techniques for biomarker analysis, such as guidelines and strategies for assay validation methods; different mathematical models that are necessary in contemporary drug discovery and development; and evaluation of new cytometry methods. Expertly curated by two practicing professionals in drug development and biotherapeutics, individual chapters are selected for novel and sound research; information is chosen based on its relevance to lab applications and clinical trials, such as the topic of selecting animal models for their relevancy to humans. The book is multifaceted, discussing the ethics and issues with biospecimens and providing an in-depth analysis to the differences between pre-clinical and clinical assay development. The book is an essential read for general readers who need an introduction to the history and background of biomarkers, and it also provides critical analyses of various new validation methods for practitioners and researchers.

Issues In Reproductive Medicine Research 2011 Edition

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Author:
Publisher: ScholarlyEditions
ISBN: 1464965145
Size: 21.46 MB
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Issues In Reproductive Medicine Research 2011 Edition by


Original Title: Issues In Reproductive Medicine Research 2011 Edition

Issues in Reproductive Medicine Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Reproductive Medicine Research. The editors have built Issues in Reproductive Medicine Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Reproductive Medicine Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Reproductive Medicine Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues In Discovery Experimental And Laboratory Medicine 2011 Edition

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Author:
Publisher: ScholarlyEditions
ISBN: 1464963509
Size: 78.46 MB
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Issues In Discovery Experimental And Laboratory Medicine 2011 Edition by


Original Title: Issues In Discovery Experimental And Laboratory Medicine 2011 Edition

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Discovery, Experimental, and Laboratory Medicine. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Discovery, Experimental, and Laboratory Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

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