Metabolic Maps

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Author: Hiroyasu Aizawa
Publisher: Elsevier
ISBN: 0080536298
Size: 14.36 MB
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Metabolic Maps by Hiroyasu Aizawa


Original Title: Metabolic Maps

People working in development of drugs, pesticides, washing detergents, etc., are obliged by law to conduct analyses of the "metabolic pathways" or "maps" for the chemical compounds that they are using or proposing. Everyone in these industries or carrying out research toward such products is therefore interested in having a reference on these compounds. Covers literature relating to degradation and metabolic profiles of molecules Draws together the literature on degradation and metabolism patterns with that on diversified conditions of the environmental systems Indicates 3D chemical structures, predicted physico-chemical parameters, logP and the SMILES chemical notations of the parent compounds to assist scientists design the lead compounds for new discovery using computer-aided technology

Metabolic Maps Of Pesticides

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Author: Hiroyasu Aizawa
Publisher: Academic Press
ISBN: 0323140750
Size: 13.49 MB
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Metabolic Maps Of Pesticides by Hiroyasu Aizawa


Original Title: Metabolic Maps Of Pesticides

Metabolic Maps of Pesticides provides a summary of investigations and drawings of the metabolic patterns on pesticides that were collected with the aid of Chemical Abstracts Service (CAS) for the years 1970-1979. Some maps were taken from the original reports, some were slightly modified for clarity, and some were tentatively drawn from descriptions in the original articles. The pesticides are classified based on their chemical structures as functional groups or based on common chemical nomenclature. The chemical classifications highlight the properties of the mother pesticides and the impact of their degenerative metabolites on the environment. Metabolic maps are provided for the following: acid amides, amidines and guanidines, anilines and nitrobenzenes, biphenyl ethers, DDT and its analogs, dithio- and thiolcarbamates, five- and six-membered heterocyclic compounds, imides, organochlorine compounds, oxime carbamates, phenoxyacetic acids, pheny ring fused five-membered heterocyclic compounds, phenyl(aryl) carbamates, phenylureas and related compounds, phosphonothiolates and phosphonothioates, phosphonates, phosphorothioamides, phosphates, phosphorothiolates, pyrethroids, pyridines, triazines, and substituted benzenes and miscellaneous compounds.

Metabolic Pathways Of Agrochemicals Herbicides And Plant Growth Regulators

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Author: David Herd Hutson
Publisher: Royal Society of Chemistry
ISBN: 9780854044948
Size: 42.98 MB
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Metabolic Pathways Of Agrochemicals Herbicides And Plant Growth Regulators by David Herd Hutson


Original Title: Metabolic Pathways Of Agrochemicals Herbicides And Plant Growth Regulators

This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.

Metabolic Pathways Of Agrochemicals Insecticides And Fungicides

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Author: Terence Robert Roberts
Publisher: Royal Society of Chemistry
ISBN: 9780854044993
Size: 27.59 MB
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Metabolic Pathways Of Agrochemicals Insecticides And Fungicides by Terence Robert Roberts


Original Title: Metabolic Pathways Of Agrochemicals Insecticides And Fungicides

Annotation Based on literature (and some unpublished work provided by agrochemical companies), this sizable single volume provides a summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants, and animals. Entries are organized by class of chemical and cover most commercially available chemicals in use today--including modulators of insect growth and behavior, rodenticides and nematicides. Introductions to each section provide an overview of the metabolism of each major class. The editors include independent consultants and researchers from JSC International Ltd., Shell Research Ltd., E.I. Du Pont de Nemours & Co., and IACR- Rothamsted. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Regulation Of Primary Metabolic Pathways In Plants

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Author: Nicholas J. Kruger
Publisher: Springer Science & Business Media
ISBN: 940114818X
Size: 78.22 MB
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Regulation Of Primary Metabolic Pathways In Plants by Nicholas J. Kruger


Original Title: Regulation Of Primary Metabolic Pathways In Plants

Over the past decade, advances in molecular biology have provided the impetus for a resurgence of interest in plant metabolism. At a general level, the potential for modifying the quantity or quality of harvestable crop products through genetic manipulation has provided an agronomic rationale for seeking a greater understanding of primary plant metabolism and its regulation. Moreover, the now facile techniques for transformation of many plant species and the consequential capacity to manipulate the amounts of specific individual enzymes within specific cell types provides an exciting direct approach for studying metabolic problems. Such transgenic plants are also becoming invaluable tools in studies at the interface between metabolism and other sub-disciplines such as physiology and ecology. The interest generated in plant metabolism by these developments has also encouraged the re-introduction of more conventional biochemical techniques for metabolic analysis. Finally, in common with other areas of cell biology, the wealth of information that can be obtained at the nucleic acid level has provided the stimulus for identification and characterisation of metabolic processes in far greater detail than previously envisaged. The result of these advances it that researchers now have the confidence to address problems in plant metabolism at levels not previously attempted. This book presents the proceedings of an international conference held on 9-11 January 1997 at St Hugh's College, Oxford under the auspices of the Phytochemical Society of Europe.

Glamm

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Glamm by


Original Title: Glamm

The Genome-Linked Application for Metabolic Maps (GLAMM) is a unified web interface for visualizing metabolic networks, reconstructing metabolic networks from annotated genome data, visualizing experimental data in the context of metabolic networks, and investigating the construction of novel, transgenic pathways. This simple, user-friendly interface is tightly integrated with the comparative genomics tools of MicrobesOnline. GLAMM is available for free to the scientific community at glamm.lbl.gov.

Enzyme Regulation In Metabolic Pathways

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Author: Lloyd Wolfinbarger
Publisher: John Wiley & Sons
ISBN: 111915538X
Size: 31.56 MB
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Enzyme Regulation In Metabolic Pathways by Lloyd Wolfinbarger


Original Title: Enzyme Regulation In Metabolic Pathways

Enzymology is the study of enzymes as protein molecules, with specific folding patterns of the amino acid polymer and unique binding sites wherein intra- and inter-molecular distances define the specificity of the molecule to attract, bind to, and change some substrate molecule. Enzyme Regulation in Metabolic Pathways shows the reader how to understand the roles of enzymes and their kinetic constants in intermediary metabolism. It provides a means of correlating data obtained in experimental studies to multiple possible mechanisms through which some enzyme may catalyze the conversion of a substrate to a product. Quasi-equilibrium assumptions are used throughout the book, keeping the rate equation derivations simple. Actual metabolic pathways with known (presumed) positive and negative regulation events are linked to these potential kinetic mechanisms using both rate equation derivations and data plots illustrating how the rate equation derivations can be used to explain the data plots. This book will be a valuable reference for students in biological sciences and biochemistry, taking a core course in enzymology.

Purine Metabolism In Man

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Author: Oded Sperling
Publisher: Springer Science & Business Media
ISBN: 146843294X
Size: 78.18 MB
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Purine Metabolism In Man by Oded Sperling


Original Title: Purine Metabolism In Man

Gout and uric acid lithiasis are known to have affected mankind for thousands of years. It is only recently, however, that great progress has been made in the understanding of the processes involved in purine metabolism and its disorders in man. The key enzymes active in the various pathways of purine synthesis and degradation have become known and their properties are the subject of intensive study. Major contributions to the knowledge of normal purine metabolism in man have derived from the study of inborn errors in patients with purine disorders, specifically complete and partial hypoxanthine-guanine phosphoribosyltransferase deficiency. Mutations of other enzymes involved in purine metabolism are being discovered. A great step forward has been made in the treatment of gout with the introduction of uricosuric drugs and more recently of the hypoxanthine analogue allopurinol, a synthetic xanthine oxidase inhibitor. Furthermore, the complex nature of the renal handling of uric acid excretion, although still posing difficult problems, appears to approach clari fication.

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