Stereoselective Synthesis

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Author: Atta-ur-Rahman
Publisher: Elsevier Science Limited
ISBN: 9780444880338
Size: 59.97 MB
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Stereoselective Synthesis by Atta-ur-Rahman


Original Title: Stereoselective Synthesis

The exciting advances achieved in the area of stereoselective synthesis in recent years are illustrated by the applications to natural product chemistry presented in this book. The third volume to be devoted to this topic, it contains contributions by many eminent chemists and describes the stereoselective and enantioselective approaches to a variety of complex and challenging natural products.

Studies In Natural Products Chemistry

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Author: Atta-ur-Rahman
Publisher: Elsevier
ISBN: 9780080541778
Size: 78.39 MB
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Studies In Natural Products Chemistry by Atta-ur-Rahman


Original Title: Studies In Natural Products Chemistry

In Volume 18 of this well-established series, Professor Atta-ur-Rahman again brings together the work of several of the world's leading authorities in organic chemistry. Their contributions demonstrate the rapid, ongoing development of this field by illustrating many of the latest advances in synthetic methods, total synthesis, structure determination, biosynthetic pathways, and biological activity. The opening chapter presents an overview of strategies for the synthesis of several classes of natural products with an emphasis on complex polycyclic systems. Subsequent chapters discuss the synthesis of specific classes of compounds, including morphine, polyketides, acetogenins, nonactic acid derivatives, complex spirocyclic ethers, ä-lactam and pyridone derivatives, inositol phosphates, sphingolipids, brassinosteroids, Hernandia lignans, and dimeric steroidal pyrazine alkaloids. Finally, the ever stronger links between chemistry and biology are reinforced by chapters on the origin and function of secondary metabolites, bioactive conformations of gastrin hormones, and immunochemistry.

Classics In Stereoselective Synthesis

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Author: Erick M. Carreira
Publisher: John Wiley & Sons
ISBN: 9783527324521
Size: 24.53 MB
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Classics In Stereoselective Synthesis by Erick M. Carreira


Original Title: Classics In Stereoselective Synthesis

This book provides a noteworthy compilation of the groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modern practitioner of synthetic organic chemistry. The general principles underlying these processes are highlighted as they form the basis for the rapid and continuing developments in the field. The work also features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the construction of stereochemically complex structures. From the contents: "Macrocyclic stereocontrol "Carbonyl addition reactions "alpha-Functionalization of enolates "Aldol and allylation reactions "Chiral acetals "Alkene hydroboration, reduction, and oxidation "Additions to C=N bonds and synthesis of amino acids "Conjugate additions "Chiral carbanions "Metal-catalyzed allylations "Cyclopropanations and CH-insertion reactions "Sigmatropic rearrangements "Diels-Alder and hetero-Diels-Alder reactions "[3+2]- and [2+2]-cycloaddition reactions

Bioactive Natural Products

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Author: Atta-ur- Rahman
Publisher: Elsevier Science
ISBN:
Size: 18.51 MB
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Bioactive Natural Products by Atta-ur- Rahman


Original Title: Bioactive Natural Products

Natural Product Chemistry continues to expand to exciting new frontiers of great importance in medicine. Written by international authorities in various fields of natural product chemistry, this latest volume in the well-established series Studies in Natural Products Chemistry contains 23 chapters, covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases. This present volume, will again be of great interest to research scientists and scholars working in the exciting field of new drug discovery. * Written by international authorities in the various fields of natural product chemistry * Contains 23 comprehensive articles covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases * Valuable source of information for research scientists and scholars in the field of new drug discovery

Metallocenes In Regio And Stereoselective Synthesis

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Author: Tamotsu Takahashi
Publisher: Springer Science & Business Media
ISBN: 9783540016069
Size: 45.19 MB
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Metallocenes In Regio And Stereoselective Synthesis by Tamotsu Takahashi


Original Title: Metallocenes In Regio And Stereoselective Synthesis

Metallocene is a well known sandwich complex with two cyclopentadienyl ligands such as ferrocene. Recently, such metallocene compounds have been found to be very characteristic and they have become very important, not only in the area of organic synthesis, but also in polymerization in industry. Metal complexes with one cyclopentadienyl ligand have also become popular as half sandwich complexes. The number of researchers in the field of metallocenes has increased rapidly. However, the origin of the characteristic reactivity of metallocenes is not fully understood. In this volume, the chemistry of metal complexes with at least one cyclopentadienyl ligand is comprehensively covered by leading experts. Reactions discussed here are (i) natural product synthesis, (ii) catalytic asymmetric synthesis, (iii) cyclization reactions, (iv)catalytic reactions, (iv) polymerization reactions and (v) carbon-carbon bond cleavage reactions. The reader will have access to useful information about the current state of metallocene chemistry.

Stereochemistry And Stereoselective Synthesis

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Author: Mih?ly N?gr?di
Publisher: John Wiley & Sons
ISBN: 3527339019
Size: 78.54 MB
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Stereochemistry And Stereoselective Synthesis by Mih?ly N?gr?di


Original Title: Stereochemistry And Stereoselective Synthesis

Written by a well-respected and experienced author, this textbook fills the gap for a concise introduction to the key concepts of organic stereochemistry and the most important classical and modern methods in stereoselective synthesis. The concepts are extensively illustrated in color, with practical examples and question-answer sets to help consolidate the reader's knowledge. In addition, animations are available from the Wiley website. A must-have for students in chemistry, biochemistry, and life sciences, as well as researchers in pharmaceutical and agrochemical companies in need of a quick introduction to the field.

Stereoselective Synthesis Of Drugs And Natural Products 2 Volume Set

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Author: Vasyl Andrushko
Publisher: John Wiley & Sons
ISBN: 1118628330
Size: 76.32 MB
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Stereoselective Synthesis Of Drugs And Natural Products 2 Volume Set by Vasyl Andrushko


Original Title: Stereoselective Synthesis Of Drugs And Natural Products 2 Volume Set

Emphasizing synthetic strategy and practice, Stereoselective Synthesis of Drugs and Natural Products features experimental procedures for stereoselective synthetic reactions applicable to drug targets and natural products. Compiling material from leading contributors into one cohesive resource, this practical resource on synthetic methodology, reaction mechanisms, and applications for medicinal chemistry and drug discovery explores strategy and interdisciplinary work, laboratory synthesis for natural products, the preparative aspects of stereoselective synthesis for drugs, natural products, and potential biologically active compounds. The text also features experimental procedures for the different reaction methods covered.

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