The Chaperonins

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Author: Robert L. Ellis
Publisher: Elsevier
ISBN: 9780080528885
Size: 70.42 MB
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The Chaperonins by Robert L. Ellis


Original Title: The Chaperonins

The first of its kind, this volume presents the latest research findings on the chaperonins, the best studied family of a class of proteins known as molecular chaperones. These findings are changing our view of some fundamental cellular processes involving proteins, especially how proteins fold into their functional conformations. Origins of the new view of protein folding Prokaryotic chaperonins Eukaryotic chaperonins Evolution of the chaperonins Refolding of denatured proteins Organelle biosynthesis Biomedical aspects

Plant Responses To Abiotic Stress

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Author: Heribert Hirt
Publisher: Springer Science & Business Media
ISBN: 9783540200376
Size: 24.87 MB
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Plant Responses To Abiotic Stress by Heribert Hirt


Original Title: Plant Responses To Abiotic Stress

Introduction; Molecular responses of higher plants to dehydration; Abscisic acid signalling; Plant responses to heat stress; Sensors of abiotic stress in Synechocystis; Oxidative stress signalling; Signal transduction in plant cold acclimation; Heavy metal signalling in plants: linking cellular and organismic responses; Molecular genetics of genotoxic stress signalling in plants; Plant salt tolerance; Transcriptome analysis in abiotic stress conditions in higher plants.

Molecular Machines

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Author: Benoît Roux
Publisher: World Scientific
ISBN: 9814343463
Size: 61.42 MB
Format: PDF, ePub, Docs
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Molecular Machines by Benoît Roux


Original Title: Molecular Machines

Molecular machines are complex biomolecules, proteins, nucleic acids, and carbohydrates that consume energy in order to perform specific functions. The concerted action of all those machines underlies all the activities of the living cell. To understand how such molecular machines are able to perform their function, it is necessary to identify the different moving parts and understand how they act together. Breaking new ground with these difficult problems is likely to require novel paradigms permitting a seamless integration of structural, dynamical and functional data from experiments and theory. The goal of this volume is to provide an introduction to the world of biological molecular machines to a broad audience of students and researchers in biosciences. Each chapter is written by leading experts to cover results from cutting-edge research, while remaining broadly accessible. The volume presents the current state of knowledge for several important systems, ranging from polymerases, the ribosome, chaperonins, the chromatophore, kinases, actin and myosin, membrane transporters, and voltage-gated ion channels, thus giving students and researches in biosciences a pedagogically integrated picture of this exciting and rapidly expanding field.

Folding And Self Assembly Of Biological Macromolecules

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Author: Noah Hardy
Publisher: World Scientific
ISBN: 9789812703057
Size: 28.24 MB
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Folding And Self Assembly Of Biological Macromolecules by Noah Hardy


Original Title: Folding And Self Assembly Of Biological Macromolecules

Organized by Alessandra Carbone ( IHeS, Bures-sur-Yvette, France ) Organized by Misha Gromov ( IHeS, Bures-sur-Yvette, France ) Organized by Fran ois K(r)p s ( CNRS-Genopole-, evry, France ) Organized by Eric Westhof ( Universit(r) Louis-Pasteur, Strasbourg, France ). This proceedings volume explores the pathways and mechanisms by which constituent residues interact and fold to yield native biological macromolecules (catalytic RNA and functional proteins), how ribosomes and other macromolecular complexes self-assemble, and relevant energetics considerations. At the week-long interactive conference, some 20 leading researchers reported their most pertinent results, confronting each other and an audience of more than 150 specialists from a wide range of scientific disciplines, including structural and molecular biology, biophysics, computer science, mathematics, and theoretical physics. The fourteen papers OCo and audience interaction OCo are edited and illustrated versions of the transcribed oral presentations. The proceedings have been selected for coverage in: . OCo Biochemistry & Biophysics Citation Index(tm). OCo Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings). OCo CC Proceedings OCo Biomedical, Biological & Agricultural Sciences. Contents: Evolution-Based Genome Analysis: An Alternative to Analyze Folding and Function in Proteins (S Benner); Conformation of Charged Polymers: Polyelectrolytes and Polyampholytes (J-F Joanny); Statistically Derived Rules for RNA Folding (M Zuker); Experimental Approaches to RNA Folding (S Woodson); Some Questions Concerning RNA Folding (F Michel); RNA Folding in Ribosome Assembly (J R Williamson); From RNA Sequences to Folding Pathways and Structures: A Perspective (H Isamber t); An Evolutionary Perspective on the Determinants of Protein Function and Assembly (O Lichtarg e); Some Residues are more Equal than Others: Application to Protein Classification and Structure Prediction (A Kister & I Gelfan d); Structure-Function Relationships in Polymerases (M Delarue); The Protein-Folding Nucleus: From Simple Models to Real Proteins (L Mirn y); Chaperonin-Mediated Protein Folding (D Thirumalai); Virus Assembly and Maturation (J E Johnson); The Animal in the Machine: Is There a Geometric Program in the Genetic Program? (A Danchin). Readership: Researchers, academics and graduate students in structural biology, cellular and molecular biology, biophysics, biochemistry and biomathematics/bioinformatics."

The Molecules Of Life Physical And Chemical Principles

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Author: John Kuriyan
Publisher: Garland Science
ISBN: 1135088926
Size: 69.81 MB
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The Molecules Of Life Physical And Chemical Principles by John Kuriyan


Original Title: The Molecules Of Life Physical And Chemical Principles

The Molecules of Life is a textbook with a new approach to physical chemistry for the life sciences. Written for undergraduates majoring in biology or health sciences, it integrates fundamental concepts in thermodynamics and kinetics with an introduction to biological mechanism at the level of molecular structure.

Extremophiles Volume I

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Author: Nicolas Glansdorff
Publisher: EOLSS Publications
ISBN: 1905839936
Size: 27.44 MB
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Extremophiles Volume I by Nicolas Glansdorff


Original Title: Extremophiles Volume I

Extremophiles is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The extremophiles represent some of the most fascinating organisms on Earth for the simple reason that they inhabit extreme environments characterized by physical and (or) chemical properties which render them totally inhospitable for most of the other organisms. The work has been sub-divided into 6 main topics related to the above mentioned environmental conditions. These topics consist of a general introduction and of several more specialized chapters that have been written by scientists prominent in the field. The chapters cover the description of the biotopes and inhabiting species, their specific characteristics as well as what we know about the molecular mechanisms which constitute the fundamentals of the resistance and adaptation of extremophiles to extreme conditions. The theme “Extremophiles” is headed by two chapters introducing the subject for non-specialists in the field, one covering the basic concepts and the other one giving an overview of the biotopes. These three volumes are aimed at the following five major target audiences: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.

Microbial Growth On C1 Compounds

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Author: Mary Lidstrom
Publisher: Springer Science & Business Media
ISBN: 9400902131
Size: 10.93 MB
Format: PDF
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Microbial Growth On C1 Compounds by Mary Lidstrom


Original Title: Microbial Growth On C1 Compounds

The 8th International Symposium on Microbial Growth on C1 Compounds was held at the Bahia Resort Hotel, San Diego, CA, 27 August-1 September, 1995. A total of 160 participants from 18 countries were registered. Eight Scientific Sessions were held in which 45 papers were presented, and 114 posters were displayed and discussed in 3 separate poster sessions. The Symposium covered a broad range of topics, including acetogenesis, methanogenesis, CO2 fixation, lithoautotrophy, carboxidotrophy, methylotrophy and methanotrophy. The theme of the Symposium was mechanistic, and under this rubric the physiology, biochemistry, molecular biology, and both applied and environmental aspects of microbial growth on C1 compounds were addressed. This Symposium Volume contains 46 chapters, including the text of an Opening Address delivered at the Symposium by J.R. Quayle. This chapter elegantly presents an historical perspective on the past 7 Symposia, in the context of major breakthroughs in the field and of what is termed `giant' topics. The reader will be pleased to see that the tradition of the past Symposia Volumes is upheld, and that both familiar and new `giant' topics are covered. This Volume presents a cutting edge view of the broad field of microbial one-carbon metabolism, and provides a valuable resource for researcher and student alike.

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